Mutation in new coronavirus increases chance of infection
A specific mutation in the new coronavirus can significantly increase its ability to infect cells, according to a study by U.S. researchers.
The research may explain why early outbreaks in some parts of the world did not end up overwhelming health systems as much as other outbreaks in New York and Italy, according to experts at Scripps Research.
The mutation, named D614G, increased the number of "spikes" on the coronavirus - which is the part that gives it its distinctive shape. Those spikes are what allow the virus to bind to and infect cells.
"The number--or density--of functional spikes on the virus is 4 or 5 times greater due to this mutation," said Hyeryun Choe, one of the senior authors of the study.
The researchers say that it is still unknown whether this small mutation affects the severity of symptoms of infected people, or increases mortality.
The researchers conducting lab experiments say that more research, including controlled studies - widely considered a gold standard for clinical trials, needs to be done to confirm their findings from test tube experiments.
Older research has showed that the new coronavirus SARS-CoV-2 is mutating and evolving as it adapts to its human hosts. The D614G mutation in particular has been flagged as an urgent concern because it appeared to be emerging as a dominant mutation.
The Scripps Research study is currently undergoing peer review and was released on Friday amid reports of its findings.
(Reporting by Manas Mishra in Bengaluru: Editing by Bernard Orr)
7 comments:
I wish I had not lost the links for what I'm about to say, and I will see if I may be able to locate those links to provide later. The links were regarding studies that supposedly prove Hydroxychloroquine and zinc ineffective or causing harm. The issue is that one study used only 25mg of Hydroxychloroquine + zinc (and proved ineffective), while another, the study showing increased mortality, used a toxic amount of hydroxychloroquine (resulting in increased mortality). Another study - published in Lancet and the New England Journal of Medicine - obviously without any vetting or even critical thinking, was called out and proven totally bogus! How any scientist could justify those studies as equivalent and disproving of Dr. Zelenko's formula is beyond me. They are not equivalent.
We know that zinc can shorten the duration of the common cold (coronavirus). Zicam proved that 2 decades ago with their original nasal swabs. The thing was that directions read you were to insert the swab just inside each nostril, pinch the nostril and swirl the swab around. I think usage was 4x per day. It worked. Zicam would stop a head cold in its tracks in 24 hours or less for me. Instruction plainly stated NOT to insert a swab deeper into the nostril nor to sniff the medication up higher into the nostril. And yet by the time less than 100 people failed to follow clear instructions.... and reported impairment of sense of smell, the swabs were pulled from the market. Zicam swabs are available under new formula that does not contain zinc. They are not very effective at all. Zicam is also available in tablet form including zinc .... however oral Zicam is upsetting to the digestive track, and fewer individuals opt for that form. There was a Zicam in the form of tiny pellets to be dissolved under the tongue, that worked nearly as well as the nasal swabs (the formula included zinc), and yet it seems to have disappeared as well. I wonder WHY? Thus a quick easy fix for the common cold became virtually unavailable.
Consider the medical cost of visits to walk in clinics, urgent care or a general physician by those seeking to shorten duration of their head cold so as not to have to miss work and other events while ill. Some fortunate individuals are able to navigate a head cold without missing a beat. Others of us may be felled for five days to a week or more. Should those who are capable of following directions for a medication be penalized because of those dim bulbs who don't or won't? It certainly is not the case regarding expensive prescription medications. Big Pharma.... pffft!
And now we have a virus more dangerous.... and again, hell no, we can't have zinc with the push (hydroxychloroquine) that gets it INTO cells to do its work.
Sounds about right to me, but the obvious push by Dr. Fauci, CDC, the FDA director, WHO, BigPharma, Medical Industrial Complex, brainwashed Americans to let Covid-19 destroy America (economy, social fabric, etc.) aside, the fact remains, the guy you voted for in 2016, Donald Trump, could turn the entire thing around, but he went off chasing far more important things, like holding large public maskless gatherings. I swan, I wonder if Trump is a secret agent of Red China or Putin Russia?
I wonder.... COULD Trump have a ghost of a chance really turning anything around when everything he's tried to do has been blocked and decried WRONG from day one? Or would he just be obstructed and blocked again? Remember when he wanted to close the border to people coming in from Wuhan? There are some powerful forces with major skin in this game. They want him OUT and they want expensive pharmaceuticals and a mandated vaccine to be the fix for Covid 19 aka SARS-CoV-2.
As for Trump and events, do you recall Nancy Pelosi's much publicized visit to China Town? As only one example of the DNC's stance re Covid early on, as compared with Trump's. Nobody's got it right yet. As for those favoring masks (I am one of those) and those refusing to wear a mask.... some of those are on the left, some on the right.
We will see how things go when the Deep State has regained full control, which barring some major event shifting the current energy stream will Take place in January.
Trump is president, he hires and fires at will. The issue is not can he turn anything around? The issue is, he has in his paw a cure for most Covid-19 infections and he let his FDA director ban that cure and get away with it. I'm looking at this politically and spiritually. Trump is the only person in America with a chance of providing that cure to America. He is on trial in God's court about that. Human courts, public opinion and otherwise, are blind to his crime, and you are one of his accomplices, since you do not call him to task.
Hehe... it don't have a direct line to the President of the U.S., unfortunately. But he is not the ONLY one "on trial in God's court" as you put it .... racking up some MAJOR KARMA in my lexicon.
We all are on trial in God's Court. You keep giving Trump a pass at this blog on his blowing the "miracle" God delivered to him via Dr. Zelenko. Nobody asked you to write to Trump, but you did vote for him, and that puts you in a different category from people who did not vote for him.
And I'm good with that
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